VARIATION IN DEMAND RESPONSE TO FDA SAFETY ALERTS

Geographic variation in drug safety: potentially unsafe prescribing of medications and prescriber responsiveness to safety alerts.

BACKGROUND Drug safety issues represent a major cause of morbidity and mortality. Alerting programs are intended to identify patients at potential risk for adverse drug reactions and may provide relevant information to prescribers to support their decision making about clinically appropriate risk reduction. Geographic differences in the incidence of drug safety issues and the responsiveness of ...

Evaluation of Facebook and Twitter Monitoring to Detect Safety Signals for Medical Products: An Analysis of Recent FDA Safety Alerts

INTRODUCTION The rapid expansion of the Internet and computing power in recent years has opened up the possibility of using social media for pharmacovigilance. While this general concept has been proposed by many, central questions remain as to whether social media can provide earlier warnings for rare and serious events than traditional signal detection from spontaneous report data. OBJECTIV...

Variation in the response of barley cultivars to nirrogen fertilizer

How well do NHS trusts react to patient safety alerts?

The study, first published in 2007, used several methods to study the nature of patient safety alerts, find out how trusts received and implemented them, assessed their impact and recommended improvements. Methods included surveys and interviews of staff at different levels from 41 NHS organizations and an in-depth study of 11 alerts.

Looking Beyond FDA Warning Letters to Explore Unforeseen Trouble Spots in eDTCA: A Response to Recent Commentaries